What is Bioinformatics?



        Bioinformatics has been defined in many ways.The most precise, in our opinion is

    "Bioinformatics is conceptualizing biology in terms of molecules   (in the sense 
     physical-chemistry)and then applying "informatics" techniques (derived from 
     disciplines such as applied Math, CS and Statistics) to understand and organize 
   the information associated  with these molecules, on a large-scale."

                                                    -by Mark Gerstein

http://www.hgmp.mrc.ac.uk/CCP11/tutorials.txt.html#11


 


            Bioinformatics is the field of science in which biology, computer science, and information technology merge into a single discipline. The ultimate goal of the field is to enable the discovery  of new biological insights as well as to create a global perspective from which unifying principles in biology can be discerned. There are three important sub-disciplines within bioinformatics:
  *  the development of new algorithms and statistics with  which to
            assess relationships among members of large data sets;
  * the analysis and interpretation of various types of data
           including nucleotide and amino acid sequences, protein domains
            and protein structures; and
  * the development and implementation of tools that enable
           efficient access and management of different types of
           information.
  http://www.ncbi.nlm.nih.gov/Education/index.html



 
 

Biological macromolecules: Introductory tutorials

 *Nucleic acid
http://ntri.tamuk.edu/cell/nucleic.html
 http://www.bmb.psu.edu/pugh/251/08.htm

 *Protein
http://ntri.tamuk.edu/homepage-ntri/lectures/protein/protein.html

 *Carbohydrate
http://www.ultranet.com/~jkimball/BiologyPages/C/Carbohydrates.html

 *Lipid
http://web.indstate.edu/thcme/mwking/lipids.html
 
 

Bioinformatics analysis & application:

Nucleic acid sequence analysis:
http://www.bmb.psu.edu/597a/students/byn1/mdm.htm
http://www.psu.edu/general/software/categories/sequence-analysis.html
http://ndbserver.rutgers.edu/NDB/archives/NAnitro/index.html
http://www.library.csi.cuny.edu/~davis/Biochem_3521/pronuclinfoweb.html#NUCLEICACID

Protein sequence analysis
http://www.nbif.org/education/tutorial.php#Tutorial1
http://ndbserver.rutgers.edu/structure-finder/tutorials/index.html
http://www.mcc.ac.uk/hpc/mantec/training/bioinformatics/tools/InetToolsBio_26.html
http://www.library.csi.cuny.edu/~davis/Biochem_3521/pronuclinfoweb.html#PROTEIN

Metabolic pathways
http://www-unix.mcs.anl.gov/compbio/PUMA/Production/puma.html

Function prediction
http://www.genome.ad.jp/manuscripts/GIW95/Oral/GIW95O05.html
http://www.cs.uga.edu/~eileen/bioinform/tsld023.htm

Structure prediction & analysis
http://www.bmm.icnet.uk/people/rob/CCP11BBS/flowchart2.html
http://ismb00.sdsc.edu/tutorials/samudrala.html
http://www.biochem.ucl.ac.uk/~shepherd/ss-intro.html#why_is
http://www.embl-heidelberg.de/predictprotein/predictprotein.html
http://www.bmerc-www.bu.edu/psa/
 
 

Data generation in bioinformatics

Genome Sequencing
genome.wustl.edu/gsc/gschmpg.html

Polymorphism
www.pam.bris.ac.uk/services/GAI/cytokine4.htm

Microarrays
www.microarrays.org/software.html
www.gene-chips.com/

Immunoinformatics
www.landesbioscience.com/journals/immunoinformatics.html
 
 

Bioinformatics resources: Databases & algorithms

http://smi-web.stanford.edu/projects/helix/mis214/
http://www.math.tau.ac.il/~shamir/algmb/algmb98.html
http://www.cs.washington.edu/education/courses/590bi/98w/
http://bigbox/bio/bin
http://www.cse.ucsc.edu/classes/cmpe177/
http://www.hgmp.mrc.ac.uk/CCP11/tutorials.txt.html#11

MISCELLANEOUS